Click here to shop - Only Available in South Africa For all official information and updates regarding COVID-19, visit the South African Department of Health's website at www.SAcoronavirus.co.za
|
|
The Prostate GlandThis endocrine gland is only found in men and is chiefly associated with sexual functioning. It is located in the pelvis, just below the bladder and is formed around part of the urethra (a membranous tube through which urine - from the bladder – and semen is discharged). Two ejaculatory ducts also pass through the prostate. These ducts originate in the vas deferens, end in the urethra and carry seminal fluid.
On this page
General information
The prostate is small at birth, but enlarges rapidly during puberty when it achieves its adult size. It is acorn shaped and is made up of muscles and glands. The prostate is divided into a number of lobes: a lobe containing mostly muscle to the front, two lobes (lateral lobes) to the sides, a lobe in the middle and a lobe to the back – where prostate cancer usually starts to manifest. When a man is sexually aroused, the gland produces an alkaline fluid, which enters the urethra through various small ducts. The fluid mixes with the rest of the fluids in the semen, which is excreted through the opening of the urethra on the tip of the penis during ejaculation. In a healthy male, this alkaline fluid comprises at least a third of the seminal fluid, and it is this fluid that gives semen its characteristic odor. Diseases of the Prostate gland
Prostatism – also known as Benign Prostatic Hyperplasia (BPH)
Definition: Non-cancerous (benign) enlargement of the prostate gland, causing difficulty in urination. The most common type of tumor found in men, responsible for a few of the urinary symptoms found in men over the age of 50. Current research shows that 20-30% of men require surgical or medical intervention for this problem before the age of 80. Causes of Prostatism
The enlargement of the prostate is not uncommon in men, which may cause later problems when urinating, as the prostate then places pressure on the urethra, which is the tube that carries the flow of urine from the bladder, through the prostate. The cause is not known, but diet and the general physical condition of the patient is speculated to play a role in the development of the condition. Symptoms of Prostatism
The above-mentioned symptoms may vary from person to person. Diagnosing ProstatismYour doctor will most probably perform a digital rectal examination and order a prostate specific antigen (PSA) blood test to check for prostate cancer. A prostate specific antigen test (PSA) will often return positive when this condition is present. It must be noted that this does not mean that any cancer is present. Treatment of ProstatismMany men display various symptoms and this leads to difficulty in diagnosis, making it difficult for a doctor to decide who should be treated and how the treatment should progress. If there is any doubt, the patient will be referred to an urologist (a specialist doctor) for an extra opinion. However, once this is diagnosed and treatment does start, it could include one of the following treatment options: Open SurgeryIf the prostate gland is very enlarged and is causing problems, open surgery may be the only option, as other treatment options may not be found to be effective. Although there are other ways to approach the surgery, the surgeon will most probably make an incision in the stomach and remove the prostate gland through this incision. Transurethral Resection of the Prostate (TURP)
This is a surgical procedure, in which a scope is inserted through the urethra at the tip of the penis, removing a part of the obstructing tissue, to improve the flow of urine. This operation is usually done under general anesthetic, where you are put under general anesthetic, or spinal anesthetic, where you still feel no pain but are still conscious. The operation usually lasts an hour, in which a resectoscope, a thin tube with a tiny camera and a wire loop carrying an electric current, is inserted into the urethra. The wire loop is used to break off pieces of the enlarged tissue causing the obstruction, while the bladder is flushed with a sterile solution to wash way all the matter that is broken off. The resectoscope is also used to stop bleeding after the matter has been broken off – a different electrical current is used to stem the bleeding. This procedure is found to be effective, although it does have the same risks associated with any type of surgical procedure. Photoselective VaporizationThis procedure is similar to TURP, but utilizes green light laser (light) energy to remove tissue. It is found that this procedure is effective when used on smaller growths and that there is less bleeding and a faster recovery time, when using this procedure. Medicinal TreatmentsOther non-invasive treatments have been developed, which use various medicines, which either relax the neck of the bladder, and/or cause the prostate to shrink. These treatments are also found to be effective, but not as effective as TURP or Photoselective vaporization. Watchful WaitingIt may be that the symptoms and condition of the prostate are not that severe and a doctor may decide to simply wait and see if the symptoms become more severe, requiring intervention. Regular check-ups will probably be recommended. Prostatitis
This complaint may account for up to 25% of all visits to the doctor, by men, complaining of problems with genital or urinary symptoms. This term actually refers to four different conditions, known as: Acute Bacterial Prostatitis Chronic Bacterial Prostatitis Chronic Prostatitis or Chronic Pelvic Pain Syndrome Asymptomatic Inflammatory Prostatitis Acute Bacterial ProstatitisAlthough very uncommon, this form of prostatitis is said to be easy to diagnose and treat. This disease usually shows symptoms such as: Chills Fever Pain in the lower back and genitals Frequent need to urinate, also at night Painful or burning sensation when urinating Body aches and pains Urinary tract infection The condition is usually treated successfully with antibiotics. Chronic Bacterial ProstatitisThis is also very uncommon, but the same symptoms as above are displayed. However, the symptoms reoccur regularly, even after treatment with antibiotics. It is found that this is caused by a defect in the prostate, which causes a continual infection. Treatment usually comprises the surgical removal of the defect and then treatment with antibiotics, although antibiotics are sometimes found not to be of benefit. Chronic Prostatitis/Chronic Pelvic Pain SyndromeThis condition is found to be most common and effects men of any age, symptoms coming and going without warning. It may present as inflammatory or non-inflammatory. Inflammatory chronic prostatitis usually shows the urine, semen and other fluids to contain cells that the body uses to fight infection, but no infecting organism. Non-inflammatory chronic prostatitis shows the fluids to contain no evidence of inflammation or infecting organism. Another condition, known as asymptomatic inflammatory prostatitis is usually diagnosed where the patient does not complain of any symptoms, but infection-fighting cells are present in his semen and urine. These cells are usually found when a doctor is looking for causes of infertility or testing for prostate cancer. Prostate Cancer
Prostate cancer is the development of malignant cells in the prostate gland, where the normally healthy cells in the gland mutate and start to multiply, causing a growth or a tumor. This mutation may spread to other body parts. If it spreads, this form of cancer seems to target the bones (usually the hips, lower spine and ribs) and lymph nodes. It is found that this form of cancer usually develops in men over the age of 50, and for this reason an examination of the prostate is usually included in a yearly medical check up. The prevalence of prostate cancer differs around the world, and research shows that it is least common in South and East Asia progressing to more common in Europe and the most common in the United States and other Western Countries. An interesting study links this difference in prevalence to the common national diet in the areas concerned: It was found that:
Post mortem and related investigation has shown that many men have prostate cancer, but do not manifest symptoms, do not undergo any therapy, but eventually die of other unrelated causes. This however does not imply that prostate tests should not be performed, and that prostate problems should not be treated, as prostate cancer may be particularly aggressive and should be treated and diagnosed as early as possible. Genetics and diet have been proven as causes of prostate cancer. Prostate cancer can be insidious, taking years to develop and may only be detected after 10 years. However, some cases manifest a very aggressive form and the cancer may spread much quicker. Symptoms of Prostate Cancer
The proliferation of malignant cells in the prostate causes the prostate to enlarge and this can put pressure on the urethra. If pressure is placed on the urethra, the following symptoms may manifest:
The symptoms may also indicate: A prostate infection (prostatitis) Benign Prostatic Hyperplasia (BPH) – a benign enlargement of the prostate. It is important to stress that you should pay your doctor a visit if you have any of these symptoms, as the earlier this is treated the better, whatever the reason. It must also be noted that all men who are over 50 years of age (but preferably any man over 40) should have a prostate cancer test regularly, regardless of whether they manifest the above-mentioned symptoms or not. Cause of Prostate Cancer
The reason for the development of cancer is still unknown and is being researched aggressively, as cancer in any form is one of the major scourges of the modern world. Why cells mutate and then begin to multiply is still a mystery and a cure seems to be a long way off. It is known, however, that there may be a genetic reason for prostate cancer, and that other environmental factors may have an influence. There seems to be a relatively small risk of you developing prostate cancer if your brother or father has or had it. Diet and lifestyle definitely play a role, as vegetarians seem to be at lower risk than meat eaters. It has been reported that a vegetarian could have a 50% less risk of contracting prostate cancer. REFERENCE 15 Current research into the influences that lifestyle and diet have on prostate cancer shows marked difference in the occurrence of this type of cancer according to the geographical area researched. A link has been established between a diet high in saturated fats, high glycaemic content and red meat and a higher occurrence of prostate cancer. This link is especially prevalent when high levels of testosterone are present, making the risk even higher. It is also found that if the level of testosterone is reduced the cancer present in the prostate is starved and is also found to reduce. Other Points of InterestProstate cancer is not infectious and cannot be transferred through sex, anal or otherwise. Although smoking causes other forms of cancer, there is as yet no established link between smoking and cancer of the prostate. Preventing Prostate Cancer
Many studies have been performed on the relation between prostate cancer and diet, and it seems that the best way to prevent prostate cancer is through eating healthily, drastically limiting the intake of red meat and animal fat and increasing the intake of soy products, fruit and raw vegetables. The effect of lycopene (contained in tomatoes, specifically tomato extract and paste) also seems to have a beneficial effect in the prevention of prostate cancer. The prevalence of prostate cancer differs around the world, and research shows that it is least common in South and East Asia progressing to more common in Europe and the most common in the United States and other Western Countries. An interesting study links this difference in prevalence to the common national diet in the areas concerned: It was found that:
Other nutritional ways to help
Notes on other studies related to the use of various food sources, vitamins and aspirin in the prevention of prostate cancer:
Diagnosing Prostate Cancer
When diagnosing prostate cancer the following techniques are mostly used:
A doctor will usually recommend a biopsy only if there is good reason to suspect prostate cancer. A GP will probably refer a patient with prostate cancer to an urologist, who specializes in the treatment of this disease. Digital Rectal Examination (DRE)
Although most men find this embarrassing and unpleasant, it is very necessary. A doctor is trained to be professional and will consider the unpleasantness and make the whole visit as comfortable as possible. The examination is usually very fast and painless. The examination will be performed after the doctor places his or her hand in a sterile glove and lubricates a finger. The doctor will then insert a finger into your rectum and feel the prostate gland to check its size or shape and if there are any lumps present. Prostate Specific Antigen (PSA) Blood Test
This antigen is produced exclusively by the prostate gland, and is found in human serum (derived from whole blood), or in whole blood. The normal total PSA concentration in the male human is 0.1-2.6 ng/ml. The word “normal” is used with caution however, as the levels of PSA may differ from one person to another. PSA levels may be raised by certain other conditions of the prostate and by other actions, causing a “false” reading. The following may raise PSA levels
Biopsy
A prostate biopsy may be recommended by your urologist, if:
Your urologist (specialist doctor) may decide to perform one of the following biopsies: A transrectal biopsy is the most common method, where a thin needle is inserted through the rectum to obtain tissue samples. A biopsy may also be taken through the urethra, using the same method, or through the perineum (the area in-between the legs, scrotum and the anus). Treatments for prostate cancer
A malignant prostate tumor, which is a development and accumulation of malignant cancerous cells in the prostate, can be localized, and this form can often be cured. The tumor is most often removed or treated by various methods. The age, state of health of the patient, the progression of the cancer and whether the cancer has spread to other body parts will be taken into consideration when developing a treatment plan. Gleason Grade
Therapy may be determined by a grade given to the tumor during a biopsy. This grading is called the “Gleason Grade” - The Gleason Grade ranges from 1 to 10 - a grade of 2 representing the least aggressive form of cancer and a grade of 10 representing the most aggressive. High grade cancers will most probably be treated aggressively by radiation or surgery, while a low grade might be left alone, with the development (if any) of the cancer being continuously observed, in a period known as “watchful waiting”. Although this is not a complete list of the types of therapy that may be used to treat prostate cancer, we found the following types to be the most common, or worthy of noting. Different therapies may be combined, for example, hormone therapy and radiotherapy:
Prostatectomy
This term is used for a surgical procedure that removes all or part of the prostate. In a radical prostatectomy, the surgeon removes the entire prostate and then reconnects the urethra to the bladder. Side Effects A skilled surgeon is required for this operation, as nerve bundles surround the prostate, and if these are damaged there is a strong possibility that erectile dysfunction will be a result – in fact it is generally found that 70% of patients undergoing this procedure experience some form of or total erectile dysfunction. Incontinence is also a common side effect of this operation. Reports show that 40% of patients are seen to experience slight incontinence (some dribbling) and 2% have to wear incontinence pads, as they loose total control of urination. While taking the side effects into consideration, surgery is still found to be the most effective way of dealing with prostate cancer, if it is localized to the prostate. Radiotherapy
This method is found to be effective on contained or localized cancer. There are many different forms of radiotherapy, varying the type of radiation used, combining it with other therapies or modulating the rays used. Many are still in the development stage or are new developments, and much research is continually being done to minimize the side effects of this treatment, and improve its effectiveness. Radiotherapy involves different types of radiation and methods of radiation, such as proton and ion beam radiation treatment, intensity modulated radiotherapy, stereotactic radiotherapy, radiosurgery, radiotherapy with oxygen etc, and your urologist may ask you to consider one of these treatments. Radiation treatment can also be adapted to suit your lifestyle, but this depends on the prognosis of your cancer and the treatment plan which will be taken to treat the cancer.
Hormone Therapy
This therapy is usually considered if the prostate cancer has spread to surrounding tissue. It is known that prostate cancer requires the hormone, testosterone, to grow and therefore, if the prostate is deprived of testosterone it will starve, causing the tumor to shrink. This treatment may not completely remove the cancer, but can be used to keep it from progressing for a number of years, easing the pain and urinary symptoms. This therapy may also be used in conjunction with other therapies, such as brachytherapy, radiotherapy and cryotherapy. Cryosurgery
This procedure can be coupled with hormone therapy, in which the size of the prostate is first reduced though inhibiting the male hormone, testosterone. This procedure is supposed to result in the death of the malignant cells in the prostate and destroys the prostate gland by freezing it. When the prostate gland has reached the required size after the hormone therapy, the patient is placed under either local or general anesthesia. Metal probes are then inserted through the perineum (the area in-between the legs, scrotum and anus) and placed on pre-determined areas of the prostate gland. Liquid nitrogen is then introduced through the probes to freeze the entire gland. An ultra-sound probe monitors the freezing process to ensure that the wall of the rectum is not frozen, while a catheter is placed in the urethra with a warming solution, to ensure that the urethra does not freeze. A Foley catheter is also inserted to ensure the flow of urine. This catheter is usually left in place for two to three weeks after the procedure. A high incidence of impotence is reported after the procedure, while another common side effect in prostate cancer treatment, incontinence is reported to not be as common as in other treatments. The formation of an anal fistula (abscess in the wall of the rectum) is reported to be a danger. Watchful WaitingProstate cancer is sometimes diagnosed, but is still in an early stage, causing little or few symptoms. A doctor may decide that, when taking everything into account, it may be advisable just to wait and monitor the cancer, without doing anything. Watchful waiting is normally followed when a man is elderly and his cancer grows so slowly that it will not alter his life expectancy. State of health and the severity of symptoms are of course also considered. Living with Prostate Cancer
Many men live with prostate cancer and die of unrelated causes, without it ever being diagnosed. However, even if no symptoms are reported, there is a very real danger of the cancer spreading to other areas of the body. The aggressiveness of prostate cancer also differs from person to person, so it is wise to go for regular check-ups and to treat the cancer as early as possible. It is found that the treatment for prostate cancer causes most of the uncomfortable effects experienced with prostate cancer, and it is these side effects that have to be coped with. Being diagnosed with cancer is a major shock and will frighten anybody. Depression
Depression is a common reaction to a diagnosis of cancer and should be faced and dealt with, as a positive mental attitude goes a long way in coping with any life threatening disease. What is found to be of great benefit is open communication. Be realistic about the changes that treating the cancer will make in your life and keep your loved ones informed about your decisions and don’t be afraid to ask for support and help. Getting involved with a support group may be a good idea – have a look on the Internet, or ask your doctor if there are any in your area. Getting involved with people who have the same problem as you can lead to an exchange of ideas and helpful information regarding treatment options and coping with the changes in your life. If you feel that you need to see a psychologist, please ask your doctor to put you in contact with one. You may need some help in coping with the shock and to help you keep your attitude positive. If you experience chronic pain, ask your doctor to refer you to a pain management centre, which will provide you with extra help in dealing with pain. Two of the major side effects of prostate treatments are incontinence and erectile dysfunction. Erectile Dysfunction
If you wish to maintain a physical relationship, it is very important to tell your doctor this. Keeping the lines of communication completely open with your doctor is essential, as this will influence the treatment plan. There are various ways to deal with erectile dysfunction, which would be known to a competent urologist. A visit to a reputable sex clinic is also an option if you are battling with erectile dysfunction. It is strongly recommended that you approach this problem through your doctor, who will help or recommend a reputable specialist – don’t buy any strange products off the web or from a sex shop, without letting your doctor know, as there is a wealth of medical knowledge available about coping and dealing with this – use your doctors expertise. Incontinence
The embarrassing problem of incontinence may be a great challenge, and you may have to use incontinence pads, but surgery may be able to rectify the problem. An incontinence specialist or nurse may have many good suggestions regarding the problem. In summary, keep communicating, be realistic and ask questions. Be prepared to change your lifestyle. Contact with other men suffering from prostate cancer will probably prove helpful. This condition has been with us for thousands of years and there is a wealth of knowledge to be tapped regarding living with this disease and coping with the side effects of treatment. Cancer can be beaten.
|
|
|